Padlock and Proximity Probes forIn Situand Array-Based Analyses: Tools for the Post-Genomic Era
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چکیده
منابع مشابه
Padlock and Proximity Probes for in Situ and Array-Based Analyses: Tools for the Post-Genomic Era
Highly specific high-throughput assays will be required to take full advantage of the accumulating information about the macromolecular composition of cells and tissues, in order to characterize biological systems in health and disease. We discuss the general problem of detection specificity and present the approach our group has taken, involving the reformatting of analogue biological informat...
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ABBREVIATIONS bp base pair cDNA complementary DNA CV coefficient of variation DNA deoxyribonucleic acid FRET fluorescence resonance energy transfer HRCA hyperbranched rolling circle amplification LN lymph node nt nucleotide OLA oligonucleotide ligation assay PCR polymerase chain reaction RCA rolling circle amplification RCR rolling circle replication RNA ribonucleic acid SCA serial circle ampli...
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Background and Rationale The scientific infrastructure in support of cotton research and improvement took a ‘giant leap forward’ with the release of the first ‘gold-standard’ cotton reference genome sequence on 5 January 2012. Later in 2012, two independent publications (Paterson et al. 2012; Wang et al. 2012) provided initial descriptions of the basic genome of cotton, with one of these also r...
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The past decade has witnessed an explosion in the growth of proteomics. The completion of numerous genome sequences, the development of powerful protein analytical technologies, as well as the design of innovative bioinformatics tools have marked the beginning of a new post-genomic era. Proteomics, the large-scale analysis of proteins in an organism, organ or organelle encompasses different asp...
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Antson, D.-O. 2001. Genotyping RNA and DNA using padlock probes. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1050. 40pp. Uppsala. ISBN 91-554-5057-1 Novel techniques are needed to investigate the genetic variation revealed in the first draft of the human genome sequence. Padlock probes are recently developed reagents, suitable fo...
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ژورنال
عنوان ژورنال: Comparative and Functional Genomics
سال: 2003
ISSN: 1531-6912,1532-6268
DOI: 10.1002/cfg.326